Multifactorial diseases, such as coronary artery disease, can be as complex as their name suggests. How much can we hope to understand about diseases with such variation in inheritance? Aa Aa Aa ...

In an age when the majority of monogenic human disease genes have been identified, one of the challenges for the coming generation of human geneticists will be to resolve complex polygenic and ...

Genetic linkage analyses on individuals suffering from a polygenic disease and their relatives help to identify chromosomal regions responsible for susceptibility and for particular traits of the ...