Most cases of Moebius syndrome are spontaneous, with no family history and no known genetic cause. In certain rare cases, the disorder has been associated with defects in chromosomes 3, 10, and 13.

For more than a century, Mendelian genetics has shaped how we think about inheritance: one gene, one trait. It is a model that still echoes through textbooks—and one that is increasingly reaching its ...

Study results regarding the clinical spectrum and inheritance pattern of GDF2 pathogenic variants suggest incomplete penetrance and/or variability of expressivity with a semi-dominant pattern of ...

Alport syndrome is a condition that develops due to mutations in three different genes – COL4A3, COL4A4 and COL4A5. The reason that the syndrome has a significant impact on the kidneys is because all ...

Evidence has been building in recent years that our diet, our habits or traumatic experiences can have consequences for the health of our children -- and even our grandchildren. The explanation that ...

Jaime Murillo, MD, explores genetic inheritance patterns of Lp(a) from childhood to adulthood, highlighting stability, factors affecting measurement, and awareness challenges among those in the health ...

These activities introduce ideas about heredity, observing the differences and similarities in a population, and modeling how inheritance works. Campers can think about organisms as systems in which ...

How much of our lifespan is written in our genes, and how much is sitting on our plates? A new analysis suggests that while ...

Touching Base is the dynamic podcast series from the editors of GEN. Each episode features a rotating case of senior editors—including John Sterling, Kevin Davies, Julianna LeMieux, Alex Phillippidis, ...

Gregor Mendel described his experiments with pea plants and proved that genes are transmitted in discrete units, with certain ...